Cocrystal drug substances have different physical properties compared to the parent drug. We no longer need to settle for the physical properties of the known forms of a compound – we have a new opportunity to create a drug product better suited to patient needs.
- Dosage, presentation and delivery route can be dramatically modified from the current marketed form
- Problems relating to poor absorption, side effects and high variability can be readdressed to improve efficacy and compliance
- Improving delivery and efficacy can open up drug uses in new diseases that were not previously possible
- Significant product differentiation can be essential for the re-development of known drugs
Numerous opportunities exist to maximise the untapped therapeutic potential of known drugs using cocrystallisation.